The Immune System

Top 5: How Viruses and Bacteria Influenced Human History

5 October 2023
Jacob Müller

Viruses may be among the most influential yet often overlooked actors in human history. Positive or not, viruses and bacteria have profoundly impacted the course of human history over the centuries.

From shaping cultures to determining the fate of empires, they have had a lasting effect on our world. The top 5: how viruses and bacteria influenced human history.

1. The black death

One of the most well-known and devastating pandemics in history, the Black Death, caused by the bacterial pathogen Yersinia pestis, struck Europe in the 14th century. The plague claimed an estimated 25 million lives, wiping out about a third of the European population. The social, economic, and political consequences were devastating, leading to profound changes in European society, including the decline of feudalism and the rise of the Renaissance.

The population decline due to the plague led to changes in the social structure of Europe. Traditional feudal structures were weakened by the loss of labor, and a growing urban middle class emerged, demanding more economic and political power.

The Black Death also had a profound cultural impact, influencing art, literature, and religious beliefs. Art from this period often reflects the fear, suffering, and death associated with the pandemic.

The pandemic also spurred medical advancements, as doctors and scientists sought to understand the causes of the plague and develop treatments. Although medical knowledge was limited at the time, the pandemic laid the groundwork for future research into infectious diseases and public health.

2. The Spanish flu

The 1918 influenza pandemic, caused by the H1N1 influenza virus, affected an estimated 500 million people worldwide and claimed approximately 50 million lives. The pandemic had far-reaching consequences for public health, the economy, and society.

The Spanish Flu led to significant economic disruption as people fell ill and died, resulting in a loss of labor and the closure of businesses. The pandemic also caused disruptions in trade and production, leading to economic downturns and unemployment.

The Spanish Flu prompted advances in medical science and public health. The pandemic highlighted the need for better infection prevention and control, contributing to the development of new vaccines, treatment methods, and public health measures.

3. Colonization of the Americas and the fall of the Aztec empire

Viruses had a significant impact on the colonization of the Americas by European powers in the 16th century. One of the most notorious examples of this viral impact was the introduction of diseases such as smallpox, measles, influenza, and typhus by European colonizers. These diseases spread rapidly among the indigenous American population, who had no immunity to these new pathogens. The results were devastating, with estimates of mortality rates reaching 80-90% in some indigenous communities.

The weakening and decimation of large segments of the indigenous population facilitated the colonization efforts of European powers, allowing them to take over territories, exploit resources, and establish their political and economic dominance.

The most infamous example is the smallpox epidemic in 1520, introduced by Spanish conquerors. This epidemic played a crucial role in the conquest of the Aztecs in the early 16th century by the Spanish conquistadors led by Hernán Cortés. When the Spaniards arrived in the Aztec empire, a large part of the Aztec civilization was devastated by the smallpox virus. The fall of the Aztec empire ensued.

Conversely, the spread of syphilis in Europe after the discovery of the New World by Columbus in 1492 is an example of a disease spread by the exchange between the Old and New Worlds.

4. Cholera and the industrial revolution

Cholera epidemics in the 19th century significantly impacted the Industrial Revolution, particularly in Great Britain, where the revolution began. This disease, caused by the bacterium Vibrio cholerae, spread rapidly in urban areas through contaminated water and had devastating effects on the population and economy. The rapid urbanization that accompanied the Industrial Revolution created overcrowded and unsanitary cities where cholera could easily spread. Poor sanitation, contaminated drinking water, and lack of hygienic practices all contributed to the outbreak and spread of the disease.

Cholera forced the government to take action on public health and sanitation. The cholera epidemics contributed to the development of public health measures such as improved water supply, sanitation, and waste disposal, ultimately improving the living conditions of the urban population.

The disease also stimulated research into the causes of infectious diseases and led to advances in epidemiology, microbiology, and public health practices.

5. Measles and the fall of the Roman empire

Some historians suggest that the measles outbreak in the 2nd century AD contributed to the fall of the Western Roman Empire by weakening the population and undermining social and political stability.

During the heyday of the Roman Empire, large parts of Europe, North Africa, and the Middle East were governed by Roman rulers. The Roman cities were densely populated and often poorly sanitized, creating ideal conditions for the spread of infectious diseases such as measles.

While measles alone were unlikely the sole cause of the fall of the Roman Empire, the epidemics weakened the population of the Roman Empire, making the empire more vulnerable to other threats, such as invasions by barbarian tribes and political instability, which ultimately led to the fall of the Roman Empire as a whole.

References

1. McNeill, William H. "Plagues and Peoples." New York: Anchor Books, 1976.

2. Diamond, Jared. "Guns, Germs, and Steel: The Fates of Human Societies." New York: W.W. Norton & Company, 1997.

3. Sommerfeld J. Plagues and peoples revisited. Basic and strategic research for ingectious disease control at the intergace in the life, health and social sciences. EMBO Rep. 2003 Jun;4 Spec No(Suppl 1):S32-4.